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Table 4 Bacteriologic and clinical outcome in per-protocol bacteriologically evaluable patients with S pneumoniae isolates resistant to penicillin G (Pen G) and/or erythromycin A (Ery A).

From: Efficacy and safety of telithromycin 800 mg once daily for 7 days in community-acquired pneumonia: an open-label, multicenter study

   MIC Susceptibility* (μg/mL)   
Subject No. Isolate (Source) TEL Pen G Ery A Bacteriologic Outcome Clinical Outcome
Subjects with single-pathogen S pneumoniae isolate
1 S pneumoniae (sputum) 0.030 (S) 0.030 (S) b>8.000 (R) Eradication Cure
2 S pneumoniae (sputum) 0.030 (S) 2.000 (R) 0.250 (S) Presumed eradication Cure
3 S pneumoniae (sputum) 0.500 (S) 2.000 (R) 8.000 (R) Presumed eradication Cure
Subjects with multiple-pathogen S pneumoniae isolate
4 S pneumoniae (sputum) 0.060 (S) 2.000 (R) 4.000 (R) Presumed eradication Cure
  M catarrhalis 0.120 (S) ND 0.120 Presumed eradication Cure
5 S pneumoniae (sputum) 0.250 (S) 2.000 (R) 8.000 (R) Presumed eradication Cure
6 S pneumoniae (sputum) 0.030 (S) 2.000 (R) 0.060 (S) Presumed eradication Cure
  H influenzae 0.002 (S) ND 1.000 Presumed eradication Cure
  M catarrhalis 0.120 (S) ND 0.250 Presumed eradication Cure
7 S pneumoniae (sputum) 0.500 (S) 2.000 (R) 8.000 (R) Presumed eradication Cure
  H influenzae 2.000 (S) ND 4.000 Presumed eradication Cure
8 S pneumoniae (blood) 1.000 (S) 0.250 (I) 8.000 (R) Presumed eradication Cure
  H influenzae 1.000 (S) ND 4.000 Presumed eradication Cure
9 S pneumoniae (blood) 1.000 (S) 0.500 (I) 8.000 (R) Presumed eradication Cure
  H influenzae 8.000 (R) ND 4.000 Presumed eradication Cure
  S aureus 0.120 (S) ND 0.500 Presumed eradication Cure
  1. MIC = minimum inhibitory concentration; ND = no data; TEL = telithromycin.
  2. *Susceptibility: S = sensitive; I = intermediate; R = resistant.
  3. Bacteriologic outcome.