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Table 3 Haematological and biochemical findings in a study of 60 patients with blood culture-proven typhoid fever

From: Clinical outcomes in typhoid fever: adverse impact of infection with nalidixic acid-resistant Salmonella typhi

Variable Frequency, overall (n = 60) NARST (n = 47) NASST (n = 13) MDR-ST (n = 22) NonMDR-ST (n = 38)
Anaemia * 19 (32) 15 (32) 4 (31) 6 (27) 13 (34)
Leucopenia * 10 (17) 8 (17) 2 (15) 4 (18) 6 (16)
Leucocytosis * 6 (10) 5 (11) 1 (8) 2 (9) 4 (11)
Thrombocytopenia * 8 (13) 6 (13) 2 (15) 3 (14) 5 (13)
AST > 2 × ULN 27 (45) 23 (49) 4 (31) 9 (41) 18 (47)
AST > 5 × ULN 8 (13) 8 (17) -- 3 (14) 5 (13)
ALT > 2 × ULN 18 (30) 16 (34) 2 (15) 6 (27) 12 (32)
ALT > 5 × ULN 4 (7) 4 (9) -- 1 (5) 3 (8)
  1. NARST = nalidixic acid-resistant Salmonella typhi
  2. NASST = nalidixic acid-sensitive Salmonella typhi
  3. MDR-ST = multidrug-resistant Salmonella typhi
  4. AST = alanine aminotransferase
  5. ALT = aspartate aminotransferase
  6. ULN = upper limit of normal
  7. MIC = minimum inhibitory concentration
  8. -- no patients in this category
  9. * defined by cut-off values as given in the text
  10. All data presented as number (%) of patients