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Table 6 Mean liver histological scores before and after interferon-alpha treatment in 51 Taiwanese chronic hepatitis C patients

From: High versus standard doses interferon-alpha in the treatment of naïve chronic hepatitis C patients in Taiwan: a 10-year cohort study

  Before treatment Follow-up† P value‡
Periportal inflammation 1.25 ± 1.47 0.84 ± 1.27 0.0419
Intralobular necrosis 1.02 ± 1.24 0.49 ± 0.92 0.0129
Portal inflammation 1.88 ± 1.24 1.16 ± 1.32 0.0030
Total necroinflammatory score 4.08 ± 2.86 2.51 ± 3.06 0.0037
Fibrosis 1.12 ± 1.09 1.10 ± 1.22 0.8485
  1. † Mean follow-up time was 1.9 year (range 0.5–5.5 years) after end of treatment.
  2. ‡ Wilcoxon's signed rank test.