You are viewing the site in preview mode

Skip to main content


Anti-Herpes Simplex Viruses activity of Camellia sinensis, member of the family Theaceae (green tea)

Article metrics

  • 1181 Accesses


Medicinal plants were shown to possess several bioactivities of which Camellia sinensis, a popularly used refreshing beverage has been reported to have immune modulating and anti viral activities. From our lab we had already shown that C. sinensis extracts possessed anti-HIV and anti-HBV activities. In the current study we evaluated its anti-HSV activities.


Aqueous and methanolic extracts of C. sinensis were tested for their anti-HSV property by CPE reduction assay on Vero cell monolayers. Cytotoxicity of the extract was measured by MTT assay.


Experiments showed that 12 µg/mL concentration of C. sinensis completely inhibited HSV-1 and 2 and the drug was found to be non toxic up to 10 mg/mL.


The study showed that C.sinesis extracts and EGCG compound are potent inhibitor of both HSV-1 and HSV-2 infection and it was found to be relatively non toxic.

Author information

Correspondence to Elanchezhiyan Manickan.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark


  • Medicinal Plant
  • Methanolic Extract
  • EGCG
  • Cell Monolayer
  • Vero Cell