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Table 4 Seven cases with human bocavirus1 single infection at high viral load associated with severe respiratory tract infections

From: Single detection of human bocavirus 1 with a high viral load in severe respiratory tract infections in previously healthy children

  Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Case 7
HBoV1 viral load (copies/mL) 3.8 × 1011 7.9 × 108 7.4 × 108 2.5 × 107 6.5 × 109 5.1 × 109 8.4 × 108
Gender Female Male Female Male Female Female Male
Age (months) 10 3 9 22 9 9 12
Underlying disease With mild anemia No Born at 34 weeks No Born at 28 weeks Born at 35 weeks With mild anemia No
Duration of symptoms before admission (days) 7 9 15 1 3 4 3
Duration of hospitalization (days) 33 12 6 5 7 8 20
Fever Yes Yes No No Yes Yes Yes
Cough Yes Yes Yes Yes Yes Yes Yes
Rhinorrhea No No Yes No Yes No Yes
Wheezing Yes No Yes Yes No Yes Yes
Dyspnea Yes Yes Yes Yes Yes Yes Yes
Diarrhea No Yes No No Yes Yes No
Weight on admission (kg) 6.0 7.3 6.0 11.0 9.0 7.0 8.0
Body temperature (°C) 38.8 37.7 37.0 37.0 38.4 37.4 39.1
Respiratory rate (/min) 30 67 58 32 50 49 62
Pulse rate (/min) 124 180 145 50 160 145 148
White blood cell (×109 cells/mL) 10.3 15.3 20.6 14.3 12.7 11.8 8.9
Neutrophil granulocyte % 61 26 34 85 68 32 68
Hemoglobin (g/l) 97 107 120 125 120 94 106
Lymphocyte % 35 70 61 12 25 67 26
Platelets (109/L) 354 420 457 352 273 499 265
Chest radiograph Yesa Yesb Yesc - Yesb Yesb Yesd
Abnormality in blood culture No No No No No No No
Bacterium in sputum culture E. coli bacteria Geleibai coli pneumonia Streptococcus pneumoniae and Haemophilus influenzae No No No Streptococcus pneumoniae
Entering the intensive care unite Yes No No No No No Yes
Complication The right lower pulmonary atelectasis No No No No No No
Final diagnosis Severe pneumonia Severe bronchiolitis Severe pneumonia Severe pneumonia Severe pneumonia Severe pneumonia Severe pneumonia
Prognosis Recover Cure Cure Cure Cure Recover Recover
  1. Note: aDouble lung inflammation, right lower pulmonary atelectasis; bDouble lung texture fuzzy, with visible flocculent shadow and lung inflation is a bit excessive; cDouble lung inflammation, light transmittance in left lung is higher than the right lung; dDouble lung lesions, the consolidation of the right lung is obvious. eThe patient in case 1 received ICU treatment for 25 days and ventilator assisted breathing for 7 days. The patient in case 7 received ICU treatment for 8 days and ventilator assisted breathing for 5 days.