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Table 3 Logistic regression of the effect of time-in-years on the prevalence of resistance with and without adjustment of risk-factors

From: Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

  Univariate   Multivariate*  
OR (95% CI) p-value OR (95% CI) p-value
Any 1.03 (0.97-1.1) 0.37 1.00 (0.93-1.08) 0.92
NRTI 1.03 (0.95-1.13) 0.44 1.01 (0.91-1.12) 0.84
NNRTI 1.18 (1.05-1.32) 0.004 1.15 (1.01-1.31) 0.03
PI 0.81 (0.72-0.92) 0.001 0.81 (0.71-0.92) 0.002
  1. *In the multivariate analyses we included the factors associated with TDRM. For Any, NRTI, and NNRTI these were Continent of origin, MSM, subtype B, recent infection as well as CD4 count for Any and NNRTI. For the PI drug class the factors associated with TDRM were log HIV-RNA load, age per 10 years, square root CD4 cell count, and recent infection.