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Table 2 HZ pain severity/interference (ZBPI) and HRQOL impact (SF-36 & EQ-5D) at initial visit: ZQOL study subgroup analyses

From: Burden of herpes zoster in the UK: findings from the zoster quality of life (ZQOL) study

Outcome variable Age Gender Antiviral Pain Severity
  Spearman’s rho P Male (n = 105) Female (n = 122) P <72 hours (n = 159) ≥ 72 hours (n = 43) p No pain (n = 23) Mild (n = 66) Moderate (n = 48) Severe (n = 79) p
Zoster Brief Pain Inventory (ZBPI)              
Pain Severity −0.0720 NS 3.4 4.0 * 3.9 3.4 NS N/A N/A N/A N/A N/A
Pain Interference −0.0173 NS 3.1 3.4 NS 3.5 2.6 * 0.7 1.7 3.5 5.3 ***
Short-Form Health Survey 36 (SF-36)              
SF-36 Physical Component Summary (PCS) −0.0903 NS 40.9 42.1 NS 43.2 46.2 NS 48.3 44.8 41.0 36.07 ***
SF-36 Mental Component Summary (MCS) 0.0840 NS 45.9 39.9 *** 41.5 46.9 NS 46.4 45.5 38.5 41.1 **
EuroQoL 5-Dimensions (EQ-5D)              
EQ-5D Self-Rated Health (SRH) −0.0295 NS 66.7 59.6 ** 63.8 73.1 NS 70.0 70.1 59.7 54.6 ***
EQ-5D Health State Index (HSI) −0.0635 NS 0.68 0.61 NS 0.63 0.70 NS 0.81 0.70 0.66 0.52 ***
  1. NS p ≥ 0.05, *p < 0.05; **p < 0.01; ***p <0.001. † = clinically meaningful difference.