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Figure 1 | BMC Infectious Diseases

Figure 1

From: Trends and correlates of HIV-1 resistance among subjects failing an antiretroviral treatment over the 2003–2012 decade in Italy

Figure 1

Trends in drug class usage and resistance at failure. Part A: Distribution of antiretroviral classes in use at time of genotyping when HIV-RNA > 1 Log copies/ml: trends of use are shown for nucleoside reverse-transcriptase inhibitors (NRTI, p < .0001*), non nucleoside reverse-transcriptase inhibitors (NNRTI, p < .0001*), protease inhibitors (PI, p < .0001*), Boosted PI (p < .0001*), antiretroviral regimens combining NRTI + NNRTI (p < .0001*), NRTI + PI (p < .0001*), NRTI + NNRTI + PI (p < .0001*). Part B: Prevalence of drug class resistance during the study period: trends of resistance are shown for NRTI (p < .0001*), NNRTI (p < .0001*), PI (p < .0001*), Boosted PI (p < .0001*), antiretroviral regimens combining NRTI + NNRTI (p < .0001*), NRTI + PI (p < .0001*), NRTI + NNRTI + PI (n.s.*). * Cochrane-Armitage test for trends.

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