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Table 1 Clinical and virological characteristics of 25 studied patients infected with genotype 1b

From: Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome

  Treatment responders SVR+, n = 12 Treatment non-responders SVR-, n = 13 P
Complete early viral response (cEVR) 12 0 -
Age (years)* 42.6 ± 17.9 50.1 ± 12.4 NS
Sex (M/F) 6/6 7/6 NS
Alanine aminotransferase levels [U/l]* 95.9 ± 74.1 109.2 ± 50.1 NS
Liver histology*, §    
Grading 1.1 ± 0.4 1.1 ± 0.4 NS
Staging 1.3 ± 1.3 1.7 ± 0.8 NS
Pretreatment viral load (IU/ml)* , ** 1.2 × 106 ± 1.2 × 106 1.5 × 106 ± 1.2× 106 NS
  1. *mean ± SD.
  2. **measured by RealTime HCV assay (Abbott), sensitivity: 12 IU/mL.
  3. §according to the METAVIR Histologic Scoring System.