Phylogenetic analysis of HVR1 populations. R - responders, NR- non-responders to treatment. Trees were inferred after application of ShoRAH error correction method on haplotypes present at a frequency of ≥5% (for populations constituting at least 3 haplotypes). The evolutionary history was inferred by using the Maximum Likelihood method based on the Tamura-Nei model . Evolutionary analyses were conducted using MEGA 5.0 .