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Table 5 Proportions of infection or clinical morbidity among household contacts of children and adults among three TIV vaccination status groups during the three consecutive influenza seasons

From: Geographical heterogeneity and influenza infection within households

  1st Year   2nd Year   3rd Year  
Children, Number (proportion) TIV(-) TIV(+) P TIV(-) Partial TIV TIV(+) P TIV(-) Partial TIV TIV(+) P
  N = 37 N = 43   N = 72 N = 38 N = 14   N = 31 N = 32 N = 74  
4-fold increase            
  H1N1 6(0.16) 6(0.14)   29(0.40) 10(0.26) 3(0.21)   13(0.42) 12(0.38) 31(0.42)  
  H3N2 4(0.11) 14(0.33)   30(0.42) 17(0.45) 4(0.29)   11(0.35) 6(0.19) 26(0.35)  
  B 4(0.11) 3(0.07)   35(0.49) 17(0.45) 7(0.50)   6(0.19) 14(0.44) 18(0.24)  
  pH1N1 - -   55(0.76) 27(0.71) 13(0.93)   - - -  
Any 4-fold increase 14(0.38) 20(0.47)   44(0.61) 23(0.61) 7(0.50)   22(0.71) 21(0.66) 52(0.70)  
Symptoms            
  Any 17(0.46) 29(0.67)   36(0.50) 22(0.58) 9(0.64)   19(0.61) 13(0.41) 37(0.50)  
  Fever 5(0.14) 14(0.33)   7(0.10) 1(0.03) 1(0.07)   3(0.10) 6(0.19) 9(0.12)  
  Fever plus any two symptoms 3(0.08) 10(0.23)   4(0.06) 0(0.00) 0(0.00)   1(0.03) 4(0.13) 7(0.09)  
Any 4-fold increase plus any symptoms 5(0.14) 15(0.35) * 24(0.33) 13(0.34) 5(0.36)   27(0.87) 24(0.75) 62(0.84)  
Adults, Number (proportion) TIV(-) TIV(+) P TIV(-) Partial TIV TIV(+) P TIV(-) Partial TIV TIV(+) P
  N = 98 N = 116   N = 222 N = 111 N = 109   N = 77 N = 74 N = 249  
Any 4-fold increase            
  H1N1 0(0.00) 2(0.02)   70(0.32) 46(0.41) 41(0.38)   10(0.13) 19(0.26) 60(0.24)  
  H3N2 9(0.09) 17(0.15)   57(0.26) 38(0.34) 41(0.38) * 3(0.04) 0(0.00) 6(0.02)  
  B 5(0.05) 3(0.03)   70(0.32) 45(0.41) 38(0.35)   4(0.05) 6(0.08) 18(0.07)  
  pH1N1 - -   109(0.49) 57(0.51) 55(0.50)   - - -  
Any 4-fold increase 14(0.14) 20(0.17)   135(0.61) 74(0.67) 75(0.69)   11(0.14) 20(0.27) 64(0.26)  
Symptoms            
  Any 43(0.44) 52(0.45)   55(0.25) 34(0.31) 39(0.36) * 30(0.39) 31(0.42) 105(0.42)  
  Fever 9(0.09) 5(0.04)   1(0.00) 4(0.04) 2(0.02)   2(0.03) 1(0.01) 7(0.03)  
  Fever plus any two symptoms 0(0.00) 1(0.01)   0(0.00) 0(0.00) 0(0.00)   1(0.01) 0(0.00) 5(0.02)  
Any 4-fold increase plus any symptoms 7(0.07) 7(0.06)   39(0.18) 24(0.22) 24(0.22)   38(0.49) 42(0.57) 131(0.53)  
  1. *P < 0.05.