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Helicobacter pyloriinfection in HIV-positive patients from the Mureş regional center
BMC Infectious Diseasesvolume 13, Article number: P75 (2013)
Helicobacter pylori, responsible for one of the most frequent infections on the globe, was reported by several literature studies to be less frequent among patients infected with human immunodeficiency virus (HIV), especially at low levels of CD4+ T-cells. The purpose of the study was to evaluate the features of Helicobacter pylori infection in HIV-positive patients from the Mureş regional center.
We performed a retrospective, descriptive study, over a 3-year period (August 2010 – August 2013), on 63 HIV-positive patients with dyspeptic symptoms, tested for Helicobacter pylori infection in the Laboratory of Infectious Diseases, Clinical County Hospital Mureş.
Seventeen (26.98%) HIV-positive patients were co-infected with Helicobacter pylori. The average level of CD4+ T-lymphocytes was 292 cells/µL in Helicobacter pylori-positive patients and 312 cells/µL in Helicobacter pylori-negative ones, which did not result in a statistically significant difference regarding the level of CD4+ T-cells (p=0.8785).
Our study showed a frequency of Helicobacter pylori-HIV co-infection of 26.98% among HIV-positive patients monitored in the regional center Mureş, without statistically significant differences regarding the level of CD4+ T-cells.
This paper is partly supported by the Sectorial Operational Programme Human Resources Development (SOP HRD), financed from the European Social Fund and by the Romanian Government under the contract number POSDRU 80641.