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HIV infected pregnant women monitored in the Adults 3 Department of the National Institute for Infectious Diseases “Prof. Dr. Matei Balş” – risk of mother to child transmission

  • Cristina Popescu1, 2Email author,
  • Mariana Mărdarescu1,
  • Raluca Dulama1,
  • Raluca Mihăilescu1,
  • Daniela Munteanu1,
  • Ruxandra Moroti1, 2,
  • Violeta Molagic1,
  • Adriana Hristea1, 2,
  • Mihaela Rădulescu1, 2,
  • Cătălin Tilişcan1, 2,
  • Raluca Năstase1,
  • Iulia Niculescu1, 2,
  • Alina Lobodan1,
  • Anca-Ruxandra Negru1,
  • Irina Lăpădat1,
  • Ligia Ionescu1 and
  • Victoria Arama1, 2
BMC Infectious Diseases201313(Suppl 1):P26

Published: 16 December 2013


Pregnant WomanCaesarean DeliveryViramuneTransmission RiskChild Infection


It was estimated that at the end of 2010 more than 34 million people are infected with HIV worldwide and 50% of them are women. After 1989 in Romania, mother-to-child transmission of HIV remains the primary way of child infection with HIV. We analyzed mother to child transmission risk factors between 2005 and 2013.


We analyzed 18 mother-infant pairs in order to establish the risk factors for HIV transmission. We performed a retrospective study of the HIV infected women monitored in the Adults 3 Department of the National Institute for Infectious Diseases “Prof. Dr. Matei Balş”.


Only 8 of the pregnant women discovered the HIV infection before childbirth and received antiviral prophylaxis: 6 with combivir and lopinavir/r, 1 with combivir and atazanavir/r and 1 with combivir and viramune. All of these patients had caesarean delivery and formula feeding for the child. All new-born were HIV negative. 10 women were diagnosed with HIV infection after the delivery: 9 had a vaginal delivery and one caesarean delivery. None of the women took chemoprophylaxis and all patients breastfed the children. 2 children were HIV positive. Both HIV positive children were born from mothers with high viral loads and low CD4 counts.


All pregnant women must be HIV-tested before delivery in order to reduce the risk of mother-to-child transmission of HIV.

Authors’ Affiliations

National Institute for Infectious Diseases “Prof. Dr. Matei Balş”, Bucharest, Romania
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania


© Popescu et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.