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Figure 4 | BMC Infectious Diseases

Figure 4

From: Novel bioinformatics strategies for prediction of directional sequence changes in influenza virus genomes and for surveillance of potentially hazardous strains

Figure 4

Time-series changes of mono- and tetranucleotide frequencies (%). The average frequency of each mononucleotide and of one tetranucleotide GAGG among strains belonging to one human subtype isolated in a specific time period was shown with a colored bar specifying the subtype (H1N1 and H3N2 colored in light blue and blue, respectively). In the case of avian (red) and swine (grey) and of human H5N1 (brown) strains, the average frequency of each mononucleotide was calculated for all strains independently of isolated years.

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