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Table 4 Relative performance of Diagnostic tests for Leishmaniasis

From: Varied spectrum of clinical presentation and mortality in a prospective registry of visceral leishmaniasis in a low endemicity area of Northern Italy

  I.F. Serology Microscopy (BM) Urinary Ag PCR - P. Blood PCR-Bone Marrow
Group (n°) POS NEG ND POS NEG ND POS NEG ND POS NEG ND POS NEG ND
Children(19) 14 (73,6%) 1 (5.3%) 4 17 (89.5%) 1 (5.3%) 1 0 0 19 1 (5.3%) 0 18 8 (42.1%) 0 11
Adults(36) 33(91,7%) 2(5,6%) 1 19(52,8%) 4(11,1%) 13 25(69,5%) 3(8.3%) 8 5(13,9%) 2(5,6%) 29 3(8,4%) 0 33
ICC(17) 15(88,2%) 1(6,7%) 1 11(64,7%) 4(23,5%) 2 8(47.0%) 2(11,8%) 7 3(17,6%) 0 14 0 0 17
ISS(19) 18(94,7%) 1(5,3%) 0 9(47,4%) 2(10,5%) 8 10(52,6%) 1(5,3%) 8 2(10,6%) 2(10,6%) 15 3(15,8%) 0 16
HIV(10) 10(100%) 0 0 3(30%) 1(10.0%) 6 7(70.0%) 0 3 2(20.0%) 1(10.0%) 7 2(20.0%) 0 8
Non-HIV(9) 8(88,9%) 1(11,1%) 0 6(66,7%) 1(11,1%) 2 3(33,3%) 1(11,1%) 5 0 1(11,1%) 8 1(11,1%) 0 8
  1. Numbers in brackets refer to the proportion (%) of patients actually evaluated by a given diagnostic method. ICC immunocompetent, ISS immunocompromised, HIV HIV infected. HIV and non-HIV are subgroups of the ISS patients.