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Table 3 Factors predictive for the tested endpoints in multivariate logistic regression analysis, including all variables given in Table 1

From: Serum cortisol predicts death and critical disease independently of CRB-65 score in community-acquired pneumonia: a prospective observational cohort study

  Mortality at 30 days Critical CAP a
Variable OR (95% CI) p-value OR (95% CI) p-value
Cortisolb 1.51 (1.13-2.01) 0.005 1.56 (1.20-2.02) 0.001
C-reactive proteinc   0.1 1.45 (1.13-1.87) 0.004
CRB65 1.62 (1.07-2.47) 0.024 3.05 (2.22-4.19) < 0.001
Congestive heart failure 2.20 (1.21-4.03) 0.010 1.96 (1.13-3.39) 0.017
Chronic renal disease 2.05 (1.03-4.04) 0.040   0.64
Malignancy 2.97 (1.50-5.89) 0.002   0.25
Age (years) 1.06 (1.03-1.09) < 0.001   0.87
Male sex 2.13 (1.13-3.99) 0.019 1.73 (1.02-2.94) 0.043
  1. a critical CAP = presence of one of the following: death occurring during antibiotic treatment, mechanical ventilation, catecholamine treatment or ICU admission
  2. b cortisol levels encoded by quartiles in nmol/l: 1. quartile 52-420; 2. quartile 420-621; 3. quartile 621-866; 4. quartile 866-9558
  3. c C-reactive protein levels encoded by quartiles in mg/L: 1. quartile < 1-18.8; 2. quartile 18.8-71.9; 3. quartile 71.9-167; 4. quartile 167-578