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Table 2 Minor and major resistance-associated mutations to protease inhibitors (PIs), nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs of HIV-1 strains from untreated pregnant women in Gabon

From: Prevalence, genetic diversity and antiretroviral drugs resistance-associated mutations among untreated HIV-1-infected pregnant women in Gabon, central Africa

Subtype n/N PIs NRTIs non-NRTIs
A 2/21 L10V - V106I, V179I
  1/21 - L210W* E138A
  2/21 - - V179I
  16/21 -/ND -/ND -/ND
D 1/1 - - V179I
F 3/5 L10V - -
  2/5 - - -
G 1/11 L10I ND ND
  1/11 L10I, V11I ND ND
  1/11 L10I, V11I, M46I* ND ND
  1/11 - V118I -
  1/11 - - A98S
  2/11 - - V179E
  4/11 - -/ND -/ND
H 2/2 -/ND - -
CRF02_AG 2/50 L10I - -
  2/50 L10V - -
  1/50 L10V, L33F - -
  1/50 L10V, T74S - -
  2/50 E35G - -
  1/50 M46I* - V90I
  1/50 - T69S -
  2/50 - - V90I
  1/50 - - V90I, V179I
  1/50 - - K101Q
  1/50 - - K103R
  2/50 - - V179I
  33/50 - -/ND -/ND
CRF06_cpx 2/2 - - -
CRF11_cpx 1/2 L10I - -
  1/2 - - -
Und 3/13 L10I - -
  1/13 L10I - V106I
  2/13 L10V -/ND -/ND
  1/13 L10V - V179I
  1/13 L10I, A71T - V179I
  1/13 - A62V -
  1/13 - V118I -
  3/13 - - -
  1. n, number of HIV-1 strains with resistance-associated mutations to PIs, NRTIs and non-NRTIs; in boldface, major mutation; -, no mutation; ND, not done; *, major mutation according to the list of investigations on transmitted ARVs resistance-associated mutations in untreated individuals [16]