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Table 1 Demographic and clinical characteristics of children with acute otitis media (AOM) before and after 7-valent pneumococcal conjugate vaccine (PCV7) implementation in France

From: Nasopharyngeal flora in children with acute otitis media before and after implementation of 7 valent pneumococcal conjugate vaccine in France

Child characteristics Before PCV7 n = 1.807 (%) After PCV7 n = 2,598 (%) p-value
Male sex' 970 (53.7) 1,376 (53.0) 0.6
Age (months), mean ± SD 14.6 ± 7.6 13.8 ± 5.1 < 0.0001
Median 12.8 13.1  
Type of care    < 0.0001
Daycare center 436 (24.1) 1032 (39.7)  
Child caregiver 530 (29.3) 811 (31.2)  
Home 841 (46.6) 754 (29.1)  
Antibiotics 3 months before enrolment 336 (57.2)* 1243 (47.9) < 0.0001
Conjunctivitis 436 (24.1) 652 (25.1) 0.5
Otalgia 1304 (83.0)** 1945 (75.0) < 0.0001
Fever (≥ 38.5°C) 671 (37.1) 1551 (60.3) < 0.0001
  1. * available for 587 patients
  2. ** available for 1,571 patients