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Table 2 Meningococcal meningitis among children aged < 60 months in China, Korea and Vietnam by age and gender group, 1999 through 2002*

From: An expanded age range for meningococcal meningitis: molecular diagnostic evidence from population-based surveillance in Asia

Characteristics PCR-confirmed Culture-confirmed Total
China Korea Vietnam Vietnam
(n = 56) (n = 92) (n = 110) (n = 10) (n = 268)b
N (%) N (%) N (%) N (%) N (%)
Age (months)
 < 1 17 (30.4) 28 (30.4) 23 (20.9) 1 (10.0) 69 (25.7)
 1-6 11 (19.6) 26 (28.3) 29 (26.4) 1 (10.0) 67 (25.0)
 7-11 5 (8.9) 4 (4.3) 21 (19.1) 4 (40.0) 34 (12.7)
 12-23 11 (19.6) 11 (12.0) 9 (8.2) 3 (30.0) 34 (12.7)
 24-35 3 (5.4) 4 (4.3) 8 (7.3) 1 (10.0) 16 (6.0)
 36-47 6 (10.7) 11 (12.0) 11 (10.0) 0 28 (10.4)
 48-59 3 (5.4) 8 (8.7) 9 (8.2) 0 20 (7.5)
Gender
 Female 13 (23.2) 31 (33.7) 53 (48.2) 5 (50.0) 102 (38.1)
 Male 43 (76.8) 61 (66.3) 57 (51.8) 5 (50.0) 166 (61.9)
Clinical features
 Lethargy/coma 19 (33.9) 8 (8.7) 60 (54.5) 4 (40.0) 91 (34.0)
 Irritability/confusion 17 (30.4) 7 (7.6) 29 (26.4) 4 (40.0) 57 (21.3)
 Nuchal rigidity 17 (30.4) 7 (7.6) 43 (39.1) 6 (60.0) 71 (26.5)
 Seizure 30 (53.6) 13 (14.1) 51 (46.4) 4 (40.0) 98 (36.6)
 Vomiting 3 (5.4) 18 (19.6) 64 (58.2) 7 (70.0) 92 (34.3)
 Bulging fontanelle 8 (14.3) 1 (1.1) 31 (28.2) 2 (20.0) 42 (15.7)
 Fever or septic appearance 29 (51.8) 80 (87.0) 82 (74.5) 9 (90.0) 200 (74.6)
Outcome
 Alive 53 (94.6) UK UK 8 (80.0) NA
 Deceased 3 (5.4) UK UK 2 (20.0) NA
Prior antibiotic usage
 Yes 23 (41.1) 53 (57.6) 78 (70.9) 10 (100.0) 164 (61.2)
  1. aSurveillance periods: China, January 1, 2000--December 31, 2002; South Korea: September 1, 1999--December 31, 2001; Vietnam: March 4, 2000-March 3, 2002.
  2. b26 specimens (China, n = 11; Vietnam, n = 15) could not be linked with the clinical database were excluded from analysis.