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Table 4 Genetic frequency of the genotypes of eight SNPs in six genes and their association with infection by influenza A/H1N1 virus

From: Pandemic influenza A/H1N1 virus infection and TNF, LTA, IL1B, IL6, IL8, and CCLpolymorphisms in Mexican population: a case–control study

Gene and genotype Genetic frequency
  A/H1N1 group AHC group p OR 95% CI ILI group p OR 95% CI
CCL1 rs2282691          
AA 0.643 0.402 0.0085 2.67 1.26-5.81 0.630 0.0096 2.53 1.23-5.30
TA 0.286 0.456     0.304    
TT 0.071 0.142     0.065    
IL1B rs16944          
GA 0.535 0.449     0.583    
GG 0.442 0.364     0.375    
AA 0.023 0.188 0.015 0.10 0.00-0.66 0.042 0.024 0.19 0.02-0.79
IL8 rs4073          
AT 0.659 0.445 0.0231 2.40 1.12-5.32 0.500    
AA 0.244 0.396     0.386    
TT 0.098 0.159     0.114    
IL6 rs1818879          
GG 0.439 0.268     0.381    
AG 0.390 0.530     0.452    
AA 0.171 0.202     0.167    
LTA rs909253          
CT 0.535 0.244 0.0004 3.56 1.68-7.54 0.540 0.00014 3.63 1.79-7.38
TT 0.302 0.488 0.0432 0.45 0.20-0.97 0.320 0.0517* 0.49 0.24-1.00
CC 0.163 0.267     0.140    
TNF          
  rs361525          
GG 0.818 0.884     0.894    
AA 0.136 0.006 0.00031 27.0 3.07-1248.77 0.000    
GA 0.045 0.110     0.106    
  rs1800629          
GG 0.932 0.946     0.911    
GA 0.068 0.054     0.089    
AA 0.000 0.000        
  rs1800750          
GG 0.789 0.949 0.0035 0.20 0.06-0.66 0.830 0.0116 0.26 0.08-0.84
AA 0.158 0.028 0.005 6.41 1.51-27.92 0.128 0.0128 5.00 1.20-21.61
GA 0.053 0.023     0.043    
  1. A/H1N1 group: patient infected with influenza A/H1N1 virus; AHC group: asymptomatic, healthy contacts; ILI group: patients with influenze-like illness; OR: odds ratio; CI: confidence interval. Results were considered statistically significant when p was <0.05.