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Table 5 Yields and NND calculated on some other recent studies that have used culture based diagnosis in TB suspects

From: High yield of culture-based diagnosis in a TB-endemic setting

  Our study Our study SN SE Monkongdee et al.[32] Boehme et al.[36] Ssengooba et al.[35]
Population HIV pos and neg SN in HIV pos and neg All HIV pos HIV pos and neg All HIV pos and SN
Pos on 1st S 377   36 561  
Pos on 2S 508   45   
Pos on 1st C 682 253 97 732 52
Pos on 2C 760 326 113   60
TB suspects tested 2537 2060 1060 1462 170
% Pos on 1st S 0.149   0.034 0.384  
% Pos on 2S 0.200   0.042   
% Pos on 1st C 0.269 0.123 0.092 0.501 0.306
% Pos on 2C 0.299 0.158 0.107   0.353
RY 2S vs 1S 1.3   1.3   
RY 1C vs 1S 1.8   2.7 1.3  
RY 1C vs 2S 1.3   2.2   
RY 2C vs 1C 1.1 1.3 1.2   1.2
AY 2S vs 1S 0.052   0.008   
AY 1C vs 1S 0.120   0.058 0.117  
AY 1C vs 2S 0.069   0.049   
AY 2C vs 1C 0.031 0.035 0.015   0.047
NND 2S vs 1S 19   118   
NND 1C vs 1S 8   17 9  
NND 1C vs 2S 15   20   
NND 2C vs 1C 33 28 66   21
NND of 1st S 7   29 3  
NND of 1st C 4 8 11 2 3
  1. Legend: S = smear, C = culture, Pos = positive, Neg = negative, RY = Relative yield, AY = Absolute yield, SE= suspect episode, NND = number needed to diagnose. In the study by Monkongdee et al. [32], yields were reported using all culture positive cases as the denominator. The results shown here use all suspects tested as the denominator.