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Table 3 Antimicrobial resistant rates of common pathogens in adult medical–surgical intensive care unit during 2000–2008

From: Surveillance on secular trends of incidence and mortality for device–associated infection in the intensive care unit setting at a tertiary medical center in Taiwan, 2000–2008: A retrospective observational study

Isolated pathogen Resistant rate (%) pvalue
  2000 2001 2002 2003 2004 2005 2006 2007 2008 Overall  
Staphylococcus aureus, n 74 47 38 26 18 7 20 17 9 256  
Methicillin–R S. aureus 94.6 91.5 100 96.2 100 85.7 100 94.1 77.8 94.9 0.414
Escherichia coli, n 12 9 9 11 8 6 7 8 8 78  
Ceftriaxone–R E. coli 50 22.2 22.2 18.2 50 33.3 28.6 62.5 50 37.2 0.314
Ceftazidime–R E. coli 25 22.2 33.3 18.2 62.5 33.3 42.9 62.5 50 37.2 0.039*
Ciprofloxacin–R E. coli 22.2 33.3 54.5 75 83.3 71.4 87.5 37.5 47.4 0.046*
ESBL E. coli 14.3 50.0 50.0 39.1 0.176
Klebsiella pneumoniae, n 9 16 9 8 17 8 14 17 11 109  
Ceftriaxone–R K. pneumoniae 66.7 18.8 55.6 75 52.9 75 71.4 88.2 36.4 58.7 0.053
Ceftazidime–R K. pneumoniae 22.2 25.0 44.4 75 76.5 75 71.4 88.2 36.4 58.7 0.002*
Ciprofloxacin–R K. pneumoniae 43.8 33.3 37.5 70.6 50 78.6 58.8 27.3 48.6 0.507
ESBL K. pneumoniae 42.9 64.7 27.3 47.6 0.532
Pseudomonas aeruginosa, n 25 14 15 16 16 23 21 23 18 171  
Ceftazidime–R P. aeruginosa 24 14.3 13.3 12.5 6.3 26.1 28.6 17.4 16.7 18.7 0.846
Cefepime–R P. aeruginosa 6.3 6.3 0 0 0 11.1 2.3 0.715
Imipenem–R P. aeruginosa 8 14.3 6.7 0 12.5 22 0 0 16.7 8.8 0.812
Acinetobacter baumannii, n 22 32 28 33 21 19 23 21 26 225  
Imipenem–R A. baumannii 0 9.4 7.1 30.3 38.1 15.8 17.4 14.3 65.4 22.2 <0.001*
  1. R: resistant, ESBL: Expanded Spectrum Beta-Lactamase producing strains.
  2. *p < 0.05.
  3. –: antibiotic susceptibilities in that year were not determined using disk diffusion tests.