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Table 2 Baseline Demographic and Medical Characteristics for CE Population: Switched vs. Not Switched from IV to Oral Therapy

From: Switch therapy in hospitalized patients with community-acquired pneumonia: Tigecycline vs. Levofloxacin

Characteristic Switched (IV to oral) No Switch (IV only)
Tigecycline N = 124 Levofloxacin N = 137 P-value Tigecycline N = 14 Levofloxacin N = 19 P-value
Age, yrs, mean ± SD 55.2 ±16.4 54.0 ± 20.4 0.613 60.1 ± 18.1 63.1 ± 17.2 0.634
Male, n (%) 64 (51.6) 83 (60.6) 0.145 9 (64.3) 13 (68.4) 0.803
Ethnic origin, n (%)    0.189    0.620
 White 80 (64.5) 87 (63.5)   9 (64.3) 9 (47.4)  
 Hispanic 29 (23.4) 34 (24.8)   5 (35.7) 7 (36.8)  
 Black 14 (11.3) 9 (6.6)   0 1 (5.3)  
 Asian 0 4 (2.9)   0 1 (5.3)  
 Other 1 (0.8) 3 (2.2)   0 1 (5.3)  
Fine Score, n (%)    0.452    0.816
 I 28 (22.6) 41 (29.9)   3 (21.4) 2 (10.5)  
 II 43 (34.7) 42 (30.7)   1 (7.1) 1 (5.3)  
 III 33 (26.6) 29 (21.2)   5 (35.7) 7 (36.8)  
 IV 20 (16.1) 25 (18.2)   5 (35.7) 9 (47.4)  
Prior antibiotic failure, n (%) 2 (1.6) 4 (3.0) 0.471 0 1 (5.3) 0.383
Therapy duration, days, mean ± SD 11.39 ± 2.0 11.26 ± 2.0 0.599 6.7 ± 3.1 6.3 ± 3.7 0.746
Presence of multilobar infiltrates, n (%) 32 (25.8) 22 (16.1) - 7 (50.0) 7 (36.8) -
Presence of altered mental status, n (%) 2 (1.6) 5 (3.6) - 0 1 (5.3) -