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Table 1 Characteristics of the patients in comparative groups: surviving vs non-surviving, ARDS vs non-ARDS

From: Soluble RAGE as a severity marker in community acquired pneumonia associated sepsis

Characteristics ARDS (n = 17) Non-ARDS (n = 13) P value Non-Surviving (n = 16) Surviving (n = 14) Pvalue
Age, mean (SD) 35.8 (11) 54 (20)   38 (14) 50 (21)  
Male sexa 9 (53) 4 (31)   10 (62.5) 3 (21)  
CURB-65 2 (1.45-2.20) 1 (0.89-2.34) .48 2 (1.49-2.51) 1 (0.94-1.92) .076
PSI class 3 (2.72-3.98) 2 (2.15-3.85) .45 4 (2.72-4.28) 2.5 (2.26-3.45) .224
APACHE II score 11 (10.18-15) 12 (7.54-13.39) .36 11.5 (9.66 - 15.47) 11.5 (8.42-12.87) .400
SOFA score 5 (4.69-7.19) 3 (2.11-4.97) .003 5.5 (4.91-7.71) 3 (2.37-4.20) .001
Mortalitya 13 (76) 3 (23)   -------------- --------------  
Renal failurea 2 (11) 0 (0)   2 (12) 0 (0)  
Shocka 4 (23) 2 (15)   6 (37) 0 (0)  
Respiratory failurea ------------ -------------   13 (81) 4 (28.5)  
Microbiological etiology, n (%)       
H1N1 S-OIV 2009a 10 (59) 4 (31)   8 (50) 6 (43)  
Seasonal Influenzaa 2 (12) 0 (0)   2 (12.5) 0 (0)  
Othersa 5 (29) 9 (69)   6 (37.5) 8 (57)  
  1. APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sepsis-Related Organ Failure Assessment; S-OIV, swine origin influenza virus
  2. aDefined according to the 1992 American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference guidelines(16). Data are mean (SD), median (CI), or n (%) when appropriate