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Table 3 Diagnostic accuracy of TST and QFT-IT in the diagnosis of active TB

From: The clinical utility of tuberculin skin test and interferon-γ release assay in the diagnosis of active tuberculosis among young adults: a prospective observational study

  TST (n = 142) QFT-IT (n = 138) P value
Sensitivity, % (95% CI) 94 (87-98) 93 (86-97) 0.79
Specificity, % (95% CI) 88 (74-96) 95 (81-99) 0.53
PPV, % (95% CI) 95 (88-98) 98 (92-99) 0.47
NPV, % (95% CI) 86 (72-94) 84 (69-93) 0.73
LR+ (95% CI) 8.1 (3.5-18.4) 17.7(4.6-68.2)  
LR- (95% CI) 0.07 (0.03-0.15) 0.07 (0.04-0.15)  
AUC (95% CI) 0.91 (0.85-0.97) 0.94 (0.89-0.99)  
  1. PPV, positive predictive value; NPV, negative predictive value, LR+, positive likelihood ratio; LR-, negative likelihood ratio; AUC, area under curve; TST, tuberculin skin test; QFT-IT, QuantiFERON® TB Gold In-Tube assay