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Table 1 Infant and maternal baseline characteristics among 737 HIV-exposed infants by infant HIV status at 12 months of life in Pune, India

From: High Rates of All-cause and Gastroenteritis-related Hospitalization Morbidity and Mortality among HIV-exposed Indian Infants

  Total N HIV- infected N = 93 HIV-exposed, uninfected N = 644 P-value
Infant Characteristics
   Female gender, n (%) 737 46 (49) 301 (47) 0.62
   Gestational age (weeks), median (IQR) 732 39 (38-40) 39 (38-40) 0.13
   APGAR at 5 minutes, median (IQR) 737 8 (8-9) 8 (8-9) 0.48
   Birth weight (grams), median (IQR) 732 2550 (2450-2950) 2650 (2400-3000) 0.29
   WHO-guided Cotrimoxazole use 737 61 (66) 247 (38) <0.001
   Any breastfeeding (days), median (IQR) 718 171 (98-276) 101 (98-182) 0.03
<4 months, n (%) 398 42 (45) 356 (57)  
4 - 6 months, n (%) 75 6 (6) 69 (11) 0.02
>6 months, n (%) 264 45 (48) 219 (34)  
   Extended dose nevirapine, n (%) 737 41 (44) 326 (51) 0.24
   Infant HAART, n (%)† 737 15 (16) n/a n/a
Maternal Characteristics
   Age (years), median (IQR) 733 24 (21-26) 23 (21-25) 0.09
   Gravidity, median (IQR) 619 2 (1-3) 2 (1-3) 0.01
   Married, n (%) 733 90 (97) 624 (97) >0.99
   Education 737    
Primary (<6 years), n (%) 294 44 (48) 250 (39)  
Secondary (6-10 years), n (%) 376 39 (42) 337 (52) 0.17
Tertiary (>10 years), n (%) 67 10 (12) 57 (9)  
   Hindu religion, n (%) 733 76 (82) 493 (77) 0.27
   Vaginal delivery, n (%) 737 77 (83) 513 (80) 0.48
   Hemoglobin* 737    
Normal (>11 g/dl), n (%) 364 36 (38.7) 328 (50.9)  
Mild Anemia (10-11 g/dl), n (%) 210 12 (12.9) 90 (14.0) 0.06
Moderate Anemia (7-10 g/dl), n (%) 140 35 (37.6) 188 (29.2)  
Severe Anemia (<7 g/dl), n (%) 23 10 (10.8) 38 (5.9)  
   CD4 cell count (cells/mm3),median (IQR)* 636 366 (217-549) 494 (334-682) 0.01
   Viral load (Log 10) (copies/ml), mean (SD)* 682 4.56 (0.9) 3.73 (1.0) <0.001
   Maternal HAART, n (%)† 737 14 (15) 48 (8) 0.01
   Maternal AZT, n (%) 737 224 (35) 24 (26) 0.09
   Maternal NVP, single-dose, n (%) 737 54 (58) 431 (67) 0.09
  1. NOTES:
  2. *Values closest to delivery are reported.
  3. †HAART use during any time of the study.
  4. ‡ P-values based on chi-square, Fisher's exact, Median test or un-paired t-test.
  5. AZT = zidovudine for PMTCT, NVP = nevirapine (intrapartum, single-dose) for PMTCT.