You are viewing the site in preview mode

Skip to main content

Advertisement

Table 2 Anti-HBs antibody responses one month after HBV challenge by pre-vaccination status (ATP Cohort for immunogenicity)

From: Lasting immune memory against hepatitis B in children after primary immunization with 4 doses of DTPa-HBV-IPV/Hib in the first and 2nd year of life

      Post challenge      
   ≥ 3.3 mIU/ml ≥ 10 mIU/ml ≥ 100 mIU/ml GMC
Pre-challenge status N n % 95% CI n % 95% CI n % 95% CI value 95% CI
<3.3 mIU/ml 21 19 90.5 [69.6; 98.8] 17 81.0 [58.1; 94.6] 11 52.4 [29.8; 74.3] 85.4 [24.7; 295.0]
≥ 3.3 mIU/ml 264 264 100 [98.6; 100] 264 100 [98.6; 100] 262 99.2 [97.3; 99.9] 12524.1 [9907.2; 15832.2]
<10 mIU/ml 42 40 95.2 [83.8; 99.4] 38 90.5 [77.4; 97.3] 31 73.8 [58.0; 86.1] 249.8 [116.9; 534.1]
≥ 10 mIU/ml 243 243 100 [98.5; 100] 243 100 [98.5; 100] 242 99.6 [97.7; 100] 16010.1 [12812.2; 20006.2]
<100 mIU/ml 151 149 98.7 [95.3; 99.8] 147 97.4 [93.4; 99.3] 139 92.1 [86.5; 95.8] 2119.3 [1475.8; 3043.4]
≥ 100 mIU/ml 134 134 100 [97.3; 100] 134 100 [97.3; 100] 134 100 [97.3; 100] 42433.2 [34084.1; 52827.5]
  1. N = number of subjects with available results. n/% = number/percentage of subjects with antibody concentrations above the specified cut-off. 95% CI = exact 95% confidence interval.