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Table 1 Anti-HBs antibody responses before and one month after challenge dose (ATP Cohort for immunogenicity)

From: Lasting immune memory against hepatitis B in children after primary immunization with 4 doses of DTPa-HBV-IPV/Hib in the first and 2nd year of life

   Seropositivity/Seroprotection rates   
   ≥ 3.3 mIU/mL ≥ 10 mIU/mL ≥ 100 mIU/mL GMC
Time point N n % [95% CI] n % [95% CI] n % [95% CI] Value [95% CI]
Pre 285 264 92.6 [89.0; 95.4] 243 85.3 [80.6; 89.2] 134 47.0 [41.1; 53.0] 83.7 [66.8; 104.9]
Post 286 284 99.3 [97.5; 99.9] 282 98.6 [96.5; 99.6] 274 95.8 [92.8; 97.8] 8656.1 [6560.7; 11420.9]
  1. GMC = geometric mean antibody concentration. N = number of subjects with available results. n/% = number/percentage of subjects with antibody concentrations above the specified cut-off. 95% CI = exact 95% confidence interval. Pre = prior to the administration of challenge dose, Post = one month after the challenge dose