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Table 1 Clinical data, origin and date of isolation of the studied strains.

From: Microsatellite typing and susceptibilities of serial Cryptococcus neoformansisolates from Cuban patients with recurrent cryptococcal meningitis

Patient Nr. Sex HIV/ Year of diagnosis Sample Isolation date Interval between each isolate in days (number) Total of days Antifungal treatment
1 Male +/1991 Blood 14/04/95 0 (08-36-09-92) 0 AmB+Flu Flu (maintenance)
    CSF 14/04/95 0 (08-36-09-75) 0 AmB+Flu Flu (maintenance)
    CSF 18/07/95 96 (08-36-10-01) 96 AmB+Flu
2 Male +/1990 CSF 05/09/95 0 (08-36-09-97) 0 Flu+Itr
    Urine 08/12/95 95 (08-36-09-70) 95 Flu
    CSF 10/01/96 34 (08-36-09-91) 129 Flu
3 Female +/1994 CSF 18/01/96 0 (08-36-09-71) 0 AmB+Flu Flu (maintenance)
    CSF 29/02/96 34 (08-36-09-72) 34 AmB+Flu
4 Male +/1995 CSF 23/04/97 0 (08-36-09-82) 0 AmB+FC+Flu
    CSF 06/05/97 14 (08-36-09-89) 14 AmB+FC+Flu
5 Male +/1998 CSF 15/04/00 0 (08-36-09-24) 0 AmB Flu (maintenance)
    CSF 26/10/00 194 (08-36-09-25) 194 AmB+FC
6 Female +/1996 CSF 12/06/00 0 (08-36-10-56) 0 AmB+FC Flu (maintenance)
    CSF 12/10/00 123 (08-36-10-52) 123 AmB Flu (maintenance)
    CSF 30/10/00 19 (08-36-10-53) 142 AmB+FC
7 Male - CSF 09/01/01 0 (08-36-09-26) 0 AmB+Itr Flu (maintenance)
    CSF 17/04/01 99 (08-36-09-30) 99 AmB+Flu Flu (maintenance)
    CSF 07/06/01 52 (08-36-09-78) 151 Flu+Itr
    Semen 19/06/01 13 (08-36-09-42) 164 Liposomal AmB