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  1. Content type: Research article

    Retaining patients on antiretroviral treatment in care is critical to sustaining the 90:90:90 vision. Nigeria has made some progress in placing HIV-positive patients on treatment. In an effort to increase acce...

    Authors: Chukwuma David Umeokonkwo, Chima Ariel Onoka, Pearl Adaoha Agu, Edmund Ndudi Ossai, Muhammad Shakir Balogun and Lawrence Ulu Ogbonnaya

    Citation: BMC Infectious Diseases 2019 19:654

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  2. Content type: Research article

    The differential diagnosis of Fever of Unknown Origin (FUO) is very extensive, and includes infectious diseases (ID), neoplasms and noninfectious inflammatory diseases (NIID). Many FUO remain undiagnosed. Fact...

    Authors: Francesco Maria Fusco, Raffaella Pisapia, Salvatore Nardiello, Stefano Domenico Cicala, Giovanni Battista Gaeta and Giuseppina Brancaccio

    Citation: BMC Infectious Diseases 2019 19:653

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  3. Content type: Research article

    Congenital Cytomegalovirus (cCMV) is the most common cause of non-genetic hearing loss in childhood. A newborn hearing screening program (NHSP) is currently running in Italy, but no universal cCMV nor statewid...

    Authors: Laura Pellegrinelli, Cristina Galli, Valeria Primache, Mirko Alde’, Enrico Fagnani, Federica Di Berardino, Diego Zanetti, Elena Pariani, Umberto Ambrosetti and Sandro Binda

    Citation: BMC Infectious Diseases 2019 19:652

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  4. Content type: Research article

    Hepatitis A, caused by the hepatitis A virus (HAV), is a vaccine preventable disease. In Low and Middle-Income Countries (LMICs), poor hygiene and sanitation conditions are the main risk factors contributing t...

    Authors: Jenna Patterson, Leila Abdullahi, Gregory D. Hussey, Rudzani Muloiwa and Benjamin M. Kagina

    Citation: BMC Infectious Diseases 2019 19:651

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  5. Content type: Research article

    This study aimed to evaluate the oral switch (OS) stewardship intervention in the intensive care unit (ICU).

    Authors: Juliano Gasparetto, Felipe Francisco Tuon, Dayana dos Santos Oliveira, Tiago Zequinao, Gabriel Rammert Pipolo, Gabriel Velloso Ribeiro, Paola Delai Benincá, June Alisson Westarb Cruz and Thyago Proenca Moraes

    Citation: BMC Infectious Diseases 2019 19:650

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  6. Content type: Technical advance

    Despite the greater sensitivity of the new dengue clinical classification proposed by the World Health Organization (WHO) in 2009, there is a need for a better definition of warning signs and clinical progress...

    Authors: Gleicy Macedo Hair, Flávio Fonseca Nobre and Patrícia Brasil

    Citation: BMC Infectious Diseases 2019 19:649

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  7. Content type: Research article

    Lassa fever virus has been enlisted as a priority pathogen of epidemic potential by the World Health organization Research and Development (WHO R & D) Blueprint. Diagnostics play a crucial role in epidemic pre...

    Authors: Noah Fongwen Takah, Polina Brangel, Priyanka Shrestha and Rosanna Peeling

    Citation: BMC Infectious Diseases 2019 19:647

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  8. Content type: Research article

    The aim of this study was to establish a set of assessment methods suitable for evaluating the complex indoor environment of hospital wards and to ascertain the composition of bacteria and microbial ecology of...

    Authors: Shao Ling and Liu Hui

    Citation: BMC Infectious Diseases 2019 19:646

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  9. Content type: Research article

    Long-term outcome of DAAs therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it in a Chinese cohort of HCV-infected kidney transplant recipients.

    Authors: Jian Zhang, Wen Sun, Jun Lin, Ye Tian, Linlin Ma, Lei Zhang, Yichen Zhu and Wei Qiu

    Citation: BMC Infectious Diseases 2019 19:645

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  10. Content type: Research article

    Given the widespread use of the Internet among men who have sex with men (MSM) and high risk of Internet-facilitated sexual behaviors, Internet-based interventions to reduce sexual risk are urgently needed.

    Authors: Weibin Cheng, Huifang Xu, Weiming Tang, Fei Zhong, Gang Meng, Zhigang Han and Jinkou Zhao

    Citation: BMC Infectious Diseases 2019 19:644

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  11. Content type: Research article

    Varicella-zoster virus (VZV) infection in children is an important public health problem in China. We performed the current study to explore the seroprevalence of VZV infection in Chinese children in order to ...

    Authors: Lin Luan, Xiaochen Shen, Jing Qiu, Yang Jing, Jingqi Zhang, Jie Wang, Jun Zhang and Chen Dong

    Citation: BMC Infectious Diseases 2019 19:643

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  12. Content type: Research article

    Cervicofacial necrotizing fasciitis (NF) is a rare life-threatening infection in the head and neck region that characteristically spreads along the fascial planes to involve subcutaneous tissues, fascia and fa...

    Authors: Arnold A. Mtenga, Boniphace M. Kalyanyama, Sira S. Owibingire, Karpal S. Sohal and Elison N.M. Simon

    Citation: BMC Infectious Diseases 2019 19:642

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  13. Content type: Research article

    The diagnoses of active smear negative PTB, remains difficult. As a result, treatment is often carried out empirically relaying on clinical criteria. The distribution and magnitude of smear negative PTB, smear...

    Authors: Waganeh Sinshaw, Abebaw Kebede, Adane Bitew, Ephrem Tesfaye, Mengistu Tadesse, Zemedu Mehamed, Bazezew Yenew, Misikir Amare, Biniyam Dagne, Getu Diriba, Ayinalem Alemu, Muluwork Getahun, Dinka Fikadu, Kassu Desta and Habteyes Hailu Tola

    Citation: BMC Infectious Diseases 2019 19:641

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  14. Content type: Research article

    The virological or clinical relapse is common in chronic hepatitis B (CHB) patients after stopping long-term nucleos(t)ide analogue (NA) therapy. Soluble growth stimulation expressed gene 2 (sST2), one of the ...

    Authors: Linqing Xie, Guichan Liao, Hongjie Chen, Muye Xia, Xuan Huang, Rong Fan, Jie Peng, Xiaoyong Zhang and Hongyan Liu

    Citation: BMC Infectious Diseases 2019 19:640

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  15. Content type: Research article

    Systemic Inflammatory Response Syndrome (SIRS) criteria are often used to evaluate the risk of sepsis and to identify in-hospital mortality among patients with suspected infection. However, utilization of the ...

    Authors: Henry Chih-Hung Tai, Chien-Chun Yeh, Yen-An Chen, Chien-Chin Hsu, Jiann-Hwa Chen, Wei-Lung Chen, Chien-Cheng Huang and Jui-Yuan Chung

    Citation: BMC Infectious Diseases 2019 19:639

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  16. Content type: Research article

    Chronic hepatitis B (CHB) is a major cause of liver-related morbidity and mortality. High HBV prevalence in immigrants and ethnic minorities and numerous barriers to healthcare access are associated with serio...

    Authors: Chul S. Hyun, Okhyun Ko, Seulgi Lee and Joseph McMenamin

    Citation: BMC Infectious Diseases 2019 19:638

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  17. Content type: Case report

    We describe a case of severe Guillain-Barre syndrome (GBS) associated with chronic active hepatitis C and mixed cryoglobulinemia (MC). To our knowledge, this association between GBS and hepatitis C virus (HCV)...

    Authors: Alexandre Chlilek, Claire Roger, Laurent Muller, Marie-Josée Carles, Robin Stephan, Didier Laureillard, Jean-Philippe Lavigne, Jean-Yves Lefrant and Albert Sotto

    Citation: BMC Infectious Diseases 2019 19:636

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  18. Content type: Research article

    The outcomes of deep-seated abscesses attributed to chronic disseminated candidiasis (CDC) in patients with hematological malignancies have rarely been reported in recent years.

    Authors: Chien-Yuan Chen, Aristine Cheng, Feng-Ming Tien, Po-Chu Lee, Hwei-Fang Tien, Wang-Huei Sheng and Yee-Chun Chen

    Citation: BMC Infectious Diseases 2019 19:635

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  19. Content type: Research article

    Elevated rates of Hepatitis C Virus (HCV) infection have been reported in epidemiological studies with people who used illicit drugs (PWUIDs) in different Brazilian regions. In Brazil’s Amazon region, studies ...

    Authors: Aldemir B. Oliveira-Filho, Francisco Junior A. Santos, Fabricio Quaresma Silva, Nairis Costa Raiol, Camila Carla S. Costa, Juliana Nadia F. Piauiense, Luisa Caricio Martins, Yasmin Maria N. Cardoso, Jeruza Ferraz F. Di Miceli, Rafael Lima Resque, Gláucia C. Silva-Oliveira, Luiz Marcelo L. Pinheiro, Luiz Fernando A. Machado, João Renato R. Pinho, José Alexandre R. Lemos, Emil Kupek…

    Citation: BMC Infectious Diseases 2019 19:634

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  20. Content type: Study protocol

    Group A Streptococcal (GAS) infections cause the autoimmune disease acute rheumatic fever (ARF), which can progress to chronic rheumatic heart disease (RHD). Treating pharyngitis caused by GAS with antibiotics...

    Authors: Julie Bennett, Nicole J. Moreland, Jane Oliver, Julian Crane, Deborah A. Williamson, Dianne Sika-Paotonu, Matire Harwood, Arlo Upton, Susan Smith, Jonathan Carapetis and Michael G. Baker

    Citation: BMC Infectious Diseases 2019 19:633

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  21. Content type: Research article

    Hepatitis B virus (HBV) testing in oral fluid samples may provide advantages in diagnosis, screening or prevalence studies, especially among individuals with venous access difficulties. This study aims to opti...

    Authors: Helena Medina Cruz, Vanessa Salete de Paula, Elisangela Ferreira da Silva, Kycia Maria Rodrigues do Ó, Flavio Augusto Pádua Milagres, Marcelo Santos Cruz, Francisco Inácio Bastos, Jurema Corrêa da Mota, Priscila Pollo-Flores, Erotildes Leal, Ana Rita Coimbra Motta-Castro, Lia Laura Lewis-Ximenez, Elisabeth Lampe and Livia Melo Villar

    Citation: BMC Infectious Diseases 2019 19:632

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  22. Content type: Research article

    In hospitalised patients with diarrhoea a positive campylobacter stool Polymerase Chain Reaction (PCR) test with negative culture results as well as Enteropathogenic Escherichia coli (EPEC) positive stool PCRs, c...

    Authors: Jan-Erik Berdal, Benoit Follin-Arbelet and Jørgen Vildershøj Bjørnholt

    Citation: BMC Infectious Diseases 2019 19:630

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  23. Content type: Research article

    Nosocomial infections and persistence of multidrug resistant biofilm forming Acinetobacter baumannii in hospitals has made it as a serious problem in healthcare settings worldwide.

    Authors: Habib Zeighami, Fatemeh Valadkhani, Reza Shapouri, Elham Samadi and Fakhri Haghi

    Citation: BMC Infectious Diseases 2019 19:629

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  24. Content type: Research article

    Tuberculosis (TB) is the infectious disease that kills the most people worldwide. The use of geoepidemiological techniques to demonstrate the dynamics of the disease in vulnerable communities is essential for ...

    Authors: Luana Seles Alves, Danielle Talita dos Santos, Marcos Augusto Moraes Arcoverde, Thais Zamboni Berra, Luiz Henrique Arroyo, Antônio Carlos Vieira Ramos, Ivaneliza Simionato de Assis, Ana Angélica Rêgo de Queiroz, Jonas Boldini Alonso, Josilene Dália Alves, Marcela Paschoal Popolin, Mellina Yamamura, Juliane de Almeida Crispim, Elma Mathias Dessunti, Pedro Fredemir Palha, Francisco Chiaraval-Neto…

    Citation: BMC Infectious Diseases 2019 19:628

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  25. Content type: Research article

    Malnutrition and diabetes are risk factors for active tuberculosis (TB), possible risk factors for latent TB infection (LTBI), and may interact to alter their effect on these outcomes. Studies to date have not...

    Authors: Rachel W. Kubiak, Sonali Sarkar, C. Robert Horsburgh, Gautam Roy, Mario Kratz, Ayiraveetil Reshma, Selby Knudsen, Padmini Salgame, Jerrold J. Ellner, Paul K. Drain and Natasha S. Hochberg

    Citation: BMC Infectious Diseases 2019 19:627

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  26. Content type: Research article

    In the United States Hepatitis C virus (HCV) viral clearance is estimated to range between 20 and 30%. The objective of this study was to estimate the frequency of HCV clearance and identify correlates of vira...

    Authors: Mabel Michille Kimble, Marjan Javanbakht, Kara W. Chew, Chrysovalantis Stafylis, Di He, Samantha Ramirez, Yeonsoo Baik, Sammy Saab and Jeffrey D. Klausner

    Citation: BMC Infectious Diseases 2019 19:626

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  27. Content type: Case report

    Visceral disseminated varicella zoster virus (VDVZV) infection is a rare disease with a high mortality rate (55%) in immunocompromised patients, but it is not yet widely recognized in the field of nephrology. ...

    Authors: Yoshitaka Furuto, Mariko Kawamura, Akio Namikawa, Hiroko Takahashi and Yuko Shibuya

    Citation: BMC Infectious Diseases 2019 19:625

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  28. Content type: Research article

    Two outbreaks of epidemic keratoconjunctivitis (EKC) occurred successively with an interval of 5 days in two primary boarding schools in Weixi Lisu Autonomous County, Diqing, and Tibetan Autonomous Prefecture,...

    Authors: Duo Li, Jie-Nan Zhou, Hong Li, Cun-Ying He, Qing-Shan Dai, Xiang-Lan Li, Jian-Fang He, Hong He, Ming-Bao Li, L I-Li Jiang, Yao-Yao Chen and Wen Xu

    Citation: BMC Infectious Diseases 2019 19:624

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  29. Content type: Research article

    Human leishmaniasis is one of the major parasitic diseases with worldwide distribution. Sri Lanka is a recently established focus of leishmaniasis caused by a variant Leishmania donovani. Early case detection and...

    Authors: Bhagya Deepachandi, Sudath Weerasinghe, Preethi Soysa, Nadira Karunaweera and Yamuna Siriwardana

    Citation: BMC Infectious Diseases 2019 19:623

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  30. Content type: Research article

    Cell-surface mucins are expressed in apical epithelial cells of the respiratory tract, and contribute a crucial part of the innate immune system. Despite anti-inflammatory or antiviral functions being revealed...

    Authors: Zhuang Gui Chen, Zhao Ni Wang, Yan Yan, Jing Liu, Ting Ting He, Kim Thye Thong, Yew Kwang Ong, Vincent T. K. Chow, Kai Sen Tan and De Yun Wang

    Citation: BMC Infectious Diseases 2019 19:622

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  31. Content type: Correction

    After publication of the original article [1], we were notified that an author’s name has been incorrectly spelled. Sedzro Divine Mensal should be replaced with Sedzro Divine Mensah.

    Authors: Yongxin Zhao, Kewang Hu, Jisheng Zhang, Yuhang Guo, Xuecai Fan, Yong Wang, Sedzro Divine Mensah and Xiaoli Zhang

    Citation: BMC Infectious Diseases 2019 19:621

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    The original article was published in BMC Infectious Diseases 2019 19:452

  32. Content type: Research article

    Escherichia coli lineage ST131 predominates across various spectra of extra-intestinal infections, including urinary tract infection (UTI). The distinctive resistance profile, diverse armamentarium of virulence f...

    Authors: Ihsan Ali, Zara Rafaque, Ibrar Ahmed, Faiza Tariq, Sarah E. Graham, Elizabeth Salzman, Betsy Foxman and Javid Iqbal Dasti

    Citation: BMC Infectious Diseases 2019 19:620

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  33. Content type: Research article

    About 10% latent tuberculosis infections (LTBI) would progress to active tuberculosis (TB), if left prophylactic therapy. Tuberculin skin test (TST) is the most widely used method for LTBI screening in the sch...

    Authors: Demin Cao, Zhiguo Zhang, Zhen Yang, Shubo Ma, Zhaogang Sun, Huijuan Duan, Baoli Zhu and Fei Zhao

    Citation: BMC Infectious Diseases 2019 19:619

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  34. Content type: Research article

    The increased transmission of multidrug-resistant (MDR) tuberculosis (TB) poses a challenge to tuberculosis prevention and control in Sri Lanka. Isoniazid (INH) is a key element of the first line anti tubercul...

    Authors: Roshanthi Eranga Karunaratne, Lahiru A. Wijenayaka, Sandya Sulochana Wijesundera, K. M. Nalin De Silva, Chamila Priyangani Adikaram and Jennifer Perera

    Citation: BMC Infectious Diseases 2019 19:618

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  35. Content type: Research article

    The major infectious diseases of hepatitis B has constituted an acute public health challenge in China. An effective and affordable HBV control model is urgently needed. A national project of Community-based C...

    Authors: Bing Ruan, Zhixin Yu, Shigui Yang, Kaijin Xu, Jingjing Ren, Jun Yao, Nanping Wu, Chengbo Yu, Min Deng, Tiansheng Xie, Ping Chen, Chencheng Wang, Yiping Li, Yanhong Zhao, Jifang Sheng, Yunde Hou…

    Citation: BMC Infectious Diseases 2019 19:617

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  36. Content type: Research article

    The point mutations in 23S rRNA gene of Mycoplasma pneumoniae (M. pneumoniae) can lead to high-level resistance to macrolides. This study aimed to evaluate allele-specific real-time PCR (ASPCR) to detect the resi...

    Authors: Dongxing Guo, Wenjuan Hu, Baoping Xu, Jingyi Li, Dan Li, Shaogang Li, Zhaoyong Wu, Ran Wei, Xiujun Tian, Kunling Shen and Deli Xin

    Citation: BMC Infectious Diseases 2019 19:616

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  37. Content type: Research article

    China contributed 8.9% of all incident cases of tuberculosis globally in 2017, and understanding the spatiotemporal distribution of pulmonary tuberculosis (PTB) in major transmission foci in the country is cri...

    Authors: Ting Li, Qu Cheng, Charles Li, Everleigh Stokes, Philip Collender, Alison Ohringer, Xintong Li, Jing Li, Jonathan L. Zelner, Song Liang, Changhong Yang, Justin V. Remais and Jin’ge He

    Citation: BMC Infectious Diseases 2019 19:615

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  38. Content type: Research article

    To evaluate the efficacy and safety of telbivudine in chronic hepatitis B women during the second and third trimesters of pregnancy.

    Authors: Li-fen Han, Jian-ming Zheng, Li-qing Zheng, Hai-bing Gao, Li-xia Chen, Qing-ling Xu, Yi-hong Chai, Xin Zhang, Chen Pan and Lv-feng Yao

    Citation: BMC Infectious Diseases 2019 19:614

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  39. Content type: Research article

    The Respiratory Syncytial Virus (RSV) A genotype ON1, which was first detected in Ontario (Canada) in 2010/11, appeared in Germany in 2011/12. Preliminary observations suggested a higher clinical severity in c...

    Authors: Andrea Streng, David Goettler, Miriam Haerlein, Lisa Lehmann, Kristina Ulrich, Christiane Prifert, Christine Krempl, Benedikt Weißbrich and Johannes G. Liese

    Citation: BMC Infectious Diseases 2019 19:613

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  40. Content type: Research article

    Tuberculosis (TB) is the leading cause of death for individuals infected with Human immunodeficiency virus (HIV). Conversely, HIV is the most important risk factor in the progression of TB from the latent to t...

    Authors: Augustus Aturinde, Mahdi Farnaghi, Petter Pilesjö and Ali Mansourian

    Citation: BMC Infectious Diseases 2019 19:612

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  41. Content type: Research article

    Bloodstream infections (BSI) due to Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-Kp) have become an important problem and they are associated with a high mortality rate. The aim of our s...

    Authors: Lucia Brescini, Gianluca Morroni, Chiara Valeriani, Sefora Castelletti, Marina Mingoia, Serena Simoni, Annamaria Masucci, Roberto Montalti, Marco Vivarelli, Andrea Giacometti and Francesco Barchiesi

    Citation: BMC Infectious Diseases 2019 19:611

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  42. Content type: Case report

    Lassa fever (LF) is a viral hemorrhagic disease caused by the Lassa virus (LASV) and endemic in West African countries with an estimation of 300,000 to 500,000 cases and 5,000 deaths annually. The Margibi Coun...

    Authors: Abyot Bekele Woyessa, Leroy Maximore, Darius Keller, John Dogba, Myer Pajibo, Kumblytee Johnson, Emmanuel Saydee, Julius Monday, Roland Tuopileyi II and Nuha Mahmoud

    Citation: BMC Infectious Diseases 2019 19:610

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  43. Content type: Research article

    Bloodstream infections (BSI) are associated with high morbidity and mortality. This scenario worsens with the emergence of drug-resistant pathogens, resulting in infections which are difficult to treat or even...

    Authors: Helena Ferreira Leal, Jailton Azevedo, Giulyana Evelyn Oliveira Silva, Angelica Maria Lima Amorim, Larissa Rangel Cabral de Roma, Ana Carolina Palmeira Arraes, Edilane Lins Gouveia, Mitermayer Galvão Reis, Ana Verena Mendes, Marcio de Oliveira Silva, Maria Goreth Barberino, Ianick Souto Martins and Joice Neves Reis

    Citation: BMC Infectious Diseases 2019 19:609

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  44. Content type: Case report

    Infectious disease prevention and control strategies require a coordinated, transnational approach. To establish core capacities of the International Health Regulations (IHR), the World Health Organization (WH...

    Authors: Mory Keïta, Georges Alfred Kizerbo, Lorenzo Subissi, Fodé Amara Traoré, Ahmadou Doré, Mohamed Fode Camara, Ahmadou Barry, Raymond Pallawo, Mamadou Oury Baldé, Nfaly Magassouba, Mamoudou Harouna Djingarey and Ibrahima Socé Fall

    Citation: BMC Infectious Diseases 2019 19:606

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  45. Content type: Research article

    Hepatitis B virus (HBV) is a hepatotropic deoxyribonucleic acid (DNA) virus which causes death. More than 300 million people have chronic liver infections globally and about 600,000 people die annually from ac...

    Authors: Abayneh Tunje Tanga, Misanew Andargie Teshome, Desta Hiko, Chaltu Fikru and Gemechu Kejela Jilo

    Citation: BMC Infectious Diseases 2019 19:602

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  46. Content type: Case report

    Despite effective antiretroviral therapy developed over the last decade, HIV infection remains a major worldwide public health problem. Recently, a promising preventive treatment has been made available for HI...

    Authors: Elise K. Van Obberghen, Delphine Viard, Alain Lafeuillade, Alexandre Civiletti, Fanny Rocher and Milou-Daniel Drici

    Citation: BMC Infectious Diseases 2019 19:601

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